Twentyfive patients with congestive heart failure were weigh

Twenty-five patients with congestive heart failure were weighed before and after receiving a
new diuretic agent, and the average weight loss (i.e. difference between the two weights) for
this sample was found to be 2 lbs. with a standard deviation of 1.38 lbs.

Assuming the weight loss to be normally distributed find a 90% confidence interval for
the mean weight loss.

If a 90% confidence interval of width 0.75 is desired and the standard deviation is 1.5
lbs., find the number of patients that will be needed.

The following percentiles of the t-distribution with 24 DF might be needed:
t.975(24) = 2.064; t.95(24) = 1.711; t.90(24) = 1.318

The following percentiles of the standard normal distribution might be needed:
z.975 = 1.96; z.95 = 1.645 ; z.90 = 1.282

Solution

A)

Note that              
Margin of Error E = t(alpha/2) * s / sqrt(n)              
Lower Bound = X - t(alpha/2) * s / sqrt(n)              
Upper Bound = X + t(alpha/2) * s / sqrt(n)              
              
where              
alpha/2 = (1 - confidence level)/2 =    0.05          
X = sample mean =    2          
t(alpha/2) = critical t for the confidence interval =    1.71088208          
s = sample standard deviation =    1.38          
n = sample size =    25          
df = n - 1 =    24          
Thus,              
Margin of Error E =    0.472203454          
Lower bound =    1.527796546          
Upper bound =    2.472203454          
              
Thus, the confidence interval is              
              
(   1.527796546   ,   2.472203454   ) [ANSWER]

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b)


Note that      
      
n = z(alpha/2)^2 s^2 / E^2      
      
where      
      
alpha/2 = (1 - confidence level)/2 =    0.05  
      
Using a table/technology,      
      
z(alpha/2) =    1.644853627  
      
Also,      
      
s = sample standard deviation =    1.38  
E = margin of error =    0.375  
      
Thus,      
      
n =    36.63955167  
      
Rounding up,      
      
n =    37   [ANSWER]

Twenty-five patients with congestive heart failure were weighed before and after receiving a new diuretic agent, and the average weight loss (i.e. difference be
Twenty-five patients with congestive heart failure were weighed before and after receiving a new diuretic agent, and the average weight loss (i.e. difference be

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