4 Sickle cell anemia is an autosomal recessive disorder Usin

4. Sickle cell anemia is an autosomal recessive disorder. Using \"S\" and \"s\" to represent the alleles, what is the genotype of a person afflicted with sickle cell anemia?

5. Two parents are apparently normal, but their daughter was born with cystic fibrosis, an inherited disorder. If cystic fibrosis is like most other human hereditary disorders, the probability of their next child being born with cystic fibrosis is _____.

Solution

4.To express sicle cell anemia in a person,genotype must be SS.But the disease remain silent in persons with Ss trait.

5.1/4th probability of having the next child with cystic fibrosis are there.it is caused by defective allele that encodes a defective chloride-channel membrane transport protein.