Rank the following genetic changes by expected effect size n

Rank the following genetic changes by expected effect size: non-synonymous variation, synonymous variation, variation in transcription factor binding site, variation in 5’UTR, copy-number variation. and explain the choice of positions

Solution

Ranking of genetic changes by expected effect size

Variation in transcription factor binding site > Synonymous Variation > Variation in 5\'UTR > non-synonymous variation > copy number variation.