An antiJsb is detected in a prenatal sample Is this antibody

An anti-Js^b is detected in a prenatal sample. Is this antibody clinically significant? What is the most probable race of this patient? What reagents would be helpful when working up this antibody?

Solution

Anti-Jsb is clinically significant. It is a rare antibody that has been related to haemolytic transfusion reactions and HDN.

It has been reported to be common among people of African descent.

Reagent anti-Jsb (KEL 7) contains antibodies of immunoglobulin class IgG as it\'s reactive component and is used for the determination of red cell antigen.