Name three hormones secreted by the endocrine pancreas What

Name three hormones secreted by the endocrine pancreas What is the normal level of blood glucose Name two effects of insulin on the liver Please give the name of the hormone which the body should secrete in response to the following Which of these statements is true (T) and which is false (F) The insulin receptor is a threonine kinase PKB (AKT) is a tyrosine kinase Ras is part of the metabolic pathway in insulin signaling Glut 3 is an insulin-dependent glucose transporter The level of glucose in the beta cell of the pancreas in normally higher than that in the blood The glucose transporter in the liver has a higher affinity for glucose that the transporter in the muscle In the absence of insulin, glycogen synthase kinase 3 (GSK3) phosphorylates and activates glycogen synthase

Solution

1.Three hormones secreted by endocrine pancreas are :

Glucagon, Insulin and Somatostatin.

2.Normal glucose level is:

Fasting before meals should be 70-99mg.dl

After food or 2hours post prandial should be less than 140mg/dl.

3.Effects of insulin on the liver is:

4.

5.

1.False.Insulin receptor is a tyrosine kinase.

2.False.PKB(AKT) is a serine /threonine kinase.

3.True

4.False. Glut 4 is an insulin dependent glucose transporter.

5.False: Beta cell has less glucose than blood and absorbs glucose when the blood glucose goes high.

6.True

7.False.In the presence of insulin,glycogen synthase kinase 3 (GSK3) phosphorylates and inactivates glycogen synthase.