How does the cell know when to start and stop translation of
How does the cell know when to start and stop translation of an mRNA molecule?
Solution
Answer:
Specific sequences direct Start and stop signals on mRNA. Translation does not simply begin at the 5´ end of the mRNA; it starts at specific initiation sites. The ribosomes bound to mRNA scan downstream of the 5´ cap until they encounter an AUG initiation codon. This is the start site of translation and protein synthesis begins. Elongation of the polypeptide chain continues until a stop codon (UAA, UAG, or UGA).
