How can knowledge of gene regulation be used to cure disease

How can knowledge of gene regulation be used to cure diseases? More than 5 sentences no plagiarism!!

Solution

Diseases which are due to inheritance of defective genes are called genetic diseases. The defective genes are the root cause of the disease. If these defective/abnormal genes can be corrected or replaced by working genes, the disease can be cured. The replacement of these defective genes is achieved by means of a vector. A vector is a carrier vehicle which carries the desired gene and delivers at the desired site. The vector encapsulates the desired genes for delivery to the cells. Attenuated or genetically engineered viruses are used as vectors.. The virus is modified by removing the disease causing components of the virus and inserting the desired genes that will be therapeutic to the patient. There are two forms of gene therapy, Somatic gene therapy and Germline gene therapy. Somatic gene therapy involves the manipulation of gene expression in cells that will be corrective to the patient but not inherited in the next generation. Germline therapy involves the genetic modification of germ cells that will pass the change on to the future generations. By these methods diseases like adenosine deaminase gene disorder, sickle cell disease can be treated.