FIND A JOURNAL PAPER BETWEEN 20002017 FOR THE following prom
FIND A JOURNAL PAPER BETWEEN 2000-2017 FOR THE following promoters
TK Promoter- CAT
RSV Promoter
Solution
1)
TK Promoter stands for Thymidine Kinase promoter, which is responsible for the regulation of thymidine kinase gene. In molecular genetics, the TK promoter is usually linked to the CAT gene ( chloramphenicol acetyltransferase) to enable the strength of promoter strength by enzyme kinetics. The following review article published in the Journal of Translational Medicine (2004) mentions about the use of this system is cell based bioassays-
Name of the article: Use of viral promoters in mammalian cell-based bioassays: How reliable?
Link to the article: https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-2-1
2)
RSV stands for Rous Sarcoma Virus. It is a retrovirus that is a causative agent for certain types of cancers. Certain viral proteins of the RSV require promoters for their expression and regulation. RSV\'s are commonly employe in various bioassays to study cancer.The following article published in Journal of Brain Research (2006) discusses about RSV promoters and role in transgene expression.
Name of the article : Assessment of CMV, RSV and SYN1 promoters and the woodchuck post-transcriptional regulatory element in adenovirus vectors for transgene expression in cortical neuronal cultures
Link to the article: http://www.sciencedirect.com/science/article/pii/S0006899306011644
