Which of the following general transcriptions factors used b

Which of the following general transcriptions factors used by RNA Polymerase II possesses Two different enzymatic activities? TFIIB TFIID TFIIE TFIIF TFIIH REEF Activity Which of the following general transcriptions factors used by RNA Polymerase II is inactive if the promoter were not to be recogized? TFIIB TFIID TFIIE TFIIF TFIIH

Solution

T.F II H is the correct option for first part, T.F II H has two different activities i.e. Helicase and Protein kinase. Helicase activity is responsible for transition from closed to open promoter complex; possibly influences promoter clearance by phosphorylation of C-terminal domain of the target subunit of RNA polymerase II.