Give an example of two Before and After Matched Pair samples

Give an example of two \"Before and After\" Matched Pair samples the difference of which a Health Professional would like to use to make a Statistical Inference and why doing such a Statistical Inference is important. The answer MUST include the target Populations of your Statistical Inference activities along with what is actually being measured

Solution

A health professional wants to determine the effect of Vitamin E on the thickness of plaque (mm) in the carotid artery. He measured the thickness of plaque (mm) in the carotid artery of 10 randomly selected patients with mild atherosclerotic disease. Two measurements are taken, thickness before treatment with Vitamin E (baseline) and after two years of taking Vitamin E daily.