G2 checkpoint Cell growth DNA synthesis O During the G2 chec

G2 checkpoint Cell growth DNA synthesis O During the G2 checkpoint, a functional p53 protein detects a DNA mutation M and C phases Cervix cell M checkpoint HPV not present p53 Formation of 2 daughter cells Replicating Mutation DNA. p53 protein is Cel growth G1 deactivated by the p53 inhibitor p53 inhibitor produced by HPV Cervix cell G, checkpoint present 2 cervix cells 3 cervix with mutated remains DNA do not healthy divide 2 With p53 3 Mutated cervix deactivated, cervix cells grow cells with mutated uncontrollably DNA successfully into a tumor divide

Solution

HPV -human papilloma viruses infect epithelial cells in human.It may cause cervical cancer.

When HPV present:- HPV producing p53 inhibitor when enters the cervix cell deactivates the p53 protein.This leads to the division of mutated cells and gets divided into two cells.The mutated cervix cells then uncontrollably grow into tumour.

When HPV not present:- In absence of HPV p53 protein gets DNA mutation present in cervix cell.Now, the cervix cells with mutated DNA do not divide thus remain healthy and no infection takes place.

 G2 checkpoint Cell growth DNA synthesis O During the G2 checkpoint, a functional p53 protein detects a DNA mutation M and C phases Cervix cell M checkpoint HPV

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