Assuming the requirements of HardyWeinberg equilibrium are m
Assuming the requirements of Hardy-Weinberg equilibrium are maintained for 1 generation, what genotypic and phenotypic frequencies would you expect?
allel frequencies are .78 and .22
expected genotype freq: P^2= .61 q^2=.05 2pq=.34
According to my chi square table, the populaiton isn\'t even in HW equilibrium
Solution
Assuming the requirements of Hardy-Weinberg equilibrium are maintained for 1 generation, what genotypic and phenotypic frequencies would you expect?
Allele frequencies are
p=0.78
and
q=0 .22
expected genotype freq: P^2= .61 q^2=.05 2pq=.34
OBSERVED
EXPECTED
(O-E)^2/E
p^2
HOMOZYGOUS DOMINANT
.78 x .78
0.6084
0.61
(0.61-0.61)^2/61 =0
2pq
HETEROZY
GOTES
2 x0.78 x0.22
0.3432
0.34
(0.34-34)^2/34 =0
q^2
HOMOZYGOUS RECESSIVE
0.22 x0.22
0.0484
0.05
(0.5-0.5)^2/0.5 =0
1
0
By using gene count method
Frequency of p allele= D+ H/2
= 0.6084 + 0.3432/2 =0.78
Frequency of Q allele= R+ H/2
= 0.0484+ 0.3432/2 =0.22
Calculate t value is less than table value at 5% level of significance
NULL HYPOTHESIS : POPULATION IN HARDY WEINBERG EQUILIBRIUM
ALTERNATIVE HYPOTHESIS : POPULATION IS NOT IN HARDY WEINBERG EQUILIBRIUM
ACEPT NULL HYPOTHEIS AND REJECT ALTERNATIVE HYPOTHEIS
THERE IS NO SIGNIFICANT DIFFERENCE BETWEEN OBSERVED AND EXPECTED FREQUENCIES
| OBSERVED | EXPECTED | (O-E)^2/E | |||
| p^2 | HOMOZYGOUS DOMINANT | .78 x .78 | 0.6084 | 0.61 | (0.61-0.61)^2/61 =0 | 
| 2pq | HETEROZY GOTES | 2 x0.78 x0.22 | 0.3432 | 0.34 | (0.34-34)^2/34 =0 | 
| q^2 | HOMOZYGOUS RECESSIVE | 0.22 x0.22 | 0.0484 | 0.05 | (0.5-0.5)^2/0.5 =0 | 
| 1 | 0 | 


