Of a lot consisting 10 items 3 items are defective How many

Of a lot consisting 10 items, 3 items are defective. How many ways can we choose different samples of 4 items from 10 items (order is not important)? If we choose 4 items randomly from above 10 items, find the probability of getting all 4 not defective. at least 1 defective. the first chosen is defective and the rest are not defective.