What roles can phosphorylation play in protein function The

What roles can phosphorylation play in protein function?

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Solution

Phosphorylation role in protein function:

Protein phosphorylation:

It is a reversible covalent modification activates or inhibits many proteins in response to environmental signals.

Protein phosphorylation can change the conformation structure and size of protein thereby altering its function.

Some proteins are regulated by the addition of a PO4 group that allows for the attraction of positive charged side chains causing a conformation change.

Reversible protein phosphorylation regulates many eukaryotic cell functions turning things on and off.

Protein in kinases added the PO4 and protein phosphate removes them.

Protein kinase:

It can capable to putting the PO4 on 3 different amino acid residues and it transfers the phosphate groups from ATP to OH groups of side chains of serine, Threonine and Tyrosine.

Protein phosphatases:

It hydrolyzes phosphorylated amino acids. It removes PO4 maybe specific for 1 or 2 reactions and maybe non-specific.