Cell division is prevented when defects in DNA structure or

Cell division is prevented when defects in DNA structure or DNA replication prevent separation of two sister chromosomes (the products of replication). Which of the following would halt cell division? Select all true statements

-DnaA protein is depleted.

-DNA ligase is not functioning.

-Single-strand binding protein is over-produced.

-DNA Polymerase III has a high error rate.

Topoisomerase IV is not functioning.

Cell division is prevented when defects in DNA structure or DNA replication prevent separation of two sister chromosomes (the products of replication). Which of the following would halt cell division? Select all true statements to get full credit. DnaA protein is depleted. DNA ligase is not functioning Single-strand binding protein is over-produced DNA Polymerase ill has a high error rate Topoisomerase IV is not functioning

Solution

Here all the statements are incorrect. Because in this case DNA replication is all ready completed and the problem is separation of two sister chromosomes. Here all the five components (DNAa protein, DNA ligase, Single -strand binding protein, DNA polymerase III, Topoisomerase) mentioned in statements are used during replication. None of the five components take part in separation of chromosomes. Although DNA ligase (mentioned in second statement) is responsible for DNA repair but this also does not take part in separation of sister chromosomes. Hence all the statements are incorrect.