please dont provide long answer DNA repair proteins such as

please don\'t provide long answer.

DNA repair proteins, such as DNA glycosylase, recognize and remove damaged nucleotides. Based on what you know about protein-DNA interactions, suggest how these repair enzymes recognize mismatches or damaged bases in double-helix DNA, and suggest what specific contacts are made between the DNA repair protein and the mismatched (or damaged) base

Solution

In procaryote like In E. coli, the methylation happens for nucleotides lets for example of A provides a covalent marker for the parental strand, and this methylation of DNA is used to discriminate parental from new progeny strands. Methylation is mostly delayed after replication and during this delay of methylation of the new DNA strand, the protein in repair system find mismatches and thus repair the base preferentially. In eukaryotes, the defective nucleotides are identified in mismatch by repair protein involve recognition of nicks which are present only in the newly synthesized DNA at 3, end superscript.