Which of the following solvents is correctly paired with a s

Which of the following solvents is correctly paired with a specific toxicity? methanol- nephrotoxicity benzene- blood dyscrasias ethylene glycol- reproductive toxicity hexane- neurotoxicity The blood-brain barrier: is not an effective barrier is a semipermeable barrier that excludes molecules greater than 40 kd is found around all parts of the brain and spinal cord is formed by having keratinocytes surround the neurons Iron: does not affect the gastrointestinal tract inhibits the synthesis of hemoglobin causes nephrosis on acute exposure accumulates in the mitochondria and leads to cell necrosis

Solution

1. D. Hexane.

Hexane is a neurotoxin affecting central nervous system producing polyneuropathy.

2. B. Is a semipermeable barrier that excludes molecules greater than 40kD.

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain extracellular fluid in the central nervous system (CNS).

The blood–brain barrier is formed by brain endothelial cells, which are connected by tight junctions.

Antibodies are too large to cross the blood–brain barrier, and only certain antibiotics are able to pass.

3. Accumulates in the mitichondria and leads to cell necrosis.

Severe iron toxicity causes impaired oxidative phosphorylation and mitochondrial dysfunction, which can result in cellular death.