Consider the following normal sequence Glyleuargglncysilephe

Consider the following normal sequence: Gly-leu-arg-gln-cys-ile-phe And the following mutant proteins. What is the nature of each mutation? Gly-leu-arg-gln Gly-leu-arg-arg-cys-ile-phe Gly-phe-lys-thr-met-gln-ile Do you consider TEs to be mutagens? Explain.

Solution

6.

a. Nonsense mutation.

Polypeptide Chain got terminated after gln.

b. Transition mutation

CAA got mutated to CGA i.e. a purine is replaced by another purine.

c. Frame shift mutation

The whole reading frame changed after reading the codon for Gly.