If only one strand of the DNA molecule is transcribed for a

If only one strand of the DNA molecule is transcribed for a particular gene, why is the other strand needed? Why is it important that both strands have all the information?

What would happen in bacterial cells that had aquired a mutation in the gene for the Trp Repressor such that the protein could no longer bind to DNA?

Solution

Ques-1: If only one strand of the DNA molecule is transcribed for a particular gene, why is the other strand needed? Why is it important that both strands have all the information?

Answer:

Genetic code is degenerate and redundant so that ff only one strand of the DNA molecule is transcribed for a particular gene, it is leading to uneven synthesis of mRNA codon because “simultaneous DNA replication “ may intervene at the time of gene expression. So that it has illustrated that transcription is going to often occur via the both strands of DNA meticulously at a particular locus. The other template strand is also needed to bind “RNA polymerase & transcription factor” to generate sense mRNA transcript. Both DNA strands are important to avoid generation of anti-sense mRNA transcript to prevent unwanted abnormal mRNA byproduct.