Homework Sourse1 which of the following statements is true regarding AIDS A
1 which of the following statements is true regarding AIDS?
A severe immune deficiency results from the progressive loss of CD4 T cells.
B at advanced stages of the disease the CD4 CD8 ration is 2:1
C leukopenia affects only T cell, all other leukocyte levels remain normal
D all of the above are true
2 which of the following does not apply to the genetic alteration that underlies sicke cell anemia?
A the resulting HbS has an altered charge that affects its solubility
B the alteration affects the mobility of HbS in an electrophoresis gel
C the overall quantity of HbS is significant reduced
D under conditions of low oxygen, the HbS will aggregate
3 Polycythemia Vera
A is an MPD
B results in elevated hematocrit levels
C is frequently associated with alteration in JAK2
D Can be treated by therapeutic phlebotomy
E all of the about are true
4
which of the following is true regarding resting endothelium?
A platelet activation is inhibited
B coagulation is inhibited
C fibrinolysis is activated
D all of the about are true
5
Shift to the left in reference to platelet formation suggest the occurrence of which of the following?
A megakaryocytes with lower ploidy
B megakaryocytes with higher ploidy
C Larger sized megakaryocytes
D ( B,C,D are correct)
6
Which of the following tests would be used for assessment of primary hemostasis?
A APTT
B closure time
C all of the above
D B and C only
7 A key function of T helper lymphocytes is to:
A Engulf pathogens by the process of phagocytosis
B Produce antibodies
C Produce cytokines that modulate the activity of other leukocytes
D Induce virus infected cells to undergo apoptosis
8. An endurance runner has just completed a 10K race. Blood is drawn for a research study on hemoglobin oxygen dissociation. What would you expect the findings to show regarding the oxygen dissociation curve?
A No changes should occur in a well-conditioned athlete
B There would be an increased oxygen affinity
C The curve will be shifted to the left
D The curve will be shifted to the right
9. Which of the following is false regarding primary hemostasis
A At high shear rates, VWF mediated platelet adhesion to collagen
B Platelets undergo dramatic shape change following adhesion to subendotheiai collagen.
C The primary plug includes platelet aggregation stabilized covalent linkages in fibrin
D Activated platelets secrete platelet agonists
10. Genetic analysis of hematopoietic neoplasms may involve
A Karyotype analysis
B FISH(fluorescence in situ hybridization)
C PCR
D DNA sequencing
E All of the above
11. Which of the following conditions are not applicable to DIC
A Consumption coagulopathy
B Altered hemostatic balance
C Vitamin K deficiency
D Whole body inflammatory response
12. Which of the following statements about hematopoietic stem cells is false
A HSCs undergo asymmetric cell division, in which one daughter cell retains self-renewal properties and the other daughter cell undergoes differentiation
B HSCs constitute about 20% of the total bone marrow nucleated cells
C HSCs spend most time in a quiescent non-dividing state
D HSCs are not morphological distinguishable from small lymphocytes
13 when of the following would not provide a source of hematopoietic stem cells for bone marrow transportation
A umbilical cord blood
B bone marrow
C blood from the spleen red pulp regions
Peripheral blood following G-GSF and GM -CSF treatment
Solution
1)A severe immune deficiency results from the progressive loss of CD4 T cells.
because less than 200 cd4 cells results in this.
2)C the overall quantity of HbS is significant reduced
because more abnormal cells (hbs cells) are formed in this .
3)B results in elevated hematocrit levels
4)D all of the about are true as all the options are true for resting epithelium
