Examine the following segment of doublestranded DNA 5ATGCCCC

Examine the following segment of double-stranded DNA:

5´-ATGCCCCGGAATGATTAGCACTCTCTCGGATCGTCGTAACGTGGTTGCCATAGTAAGA-3´ (This is the underlined strand)

3´-TACGGGGCCTTACTAATCGTGAGAGAGCCTAGCAGCATTGCACCAACGGCTACATTCT-5´

Assume that a replication bubble forms at the site of the bolded bases. As replication proceeds towards the right of the page, the new strand that is identical to the boldedand underlined strand is the “lagging strand.”

True or False?

Solution

True as the DNA polymerase recognize 3-5 strand direction as a leading strand and produces the DNA is 5-3 direction. So the given strand is 3-5 so it will produce a 5-3 strand direction which will now behave as a lagging strand...!!