QUESTION 4 US FDA risk communication guidance on mercury and

QUESTION 4

         US FDA risk communication guidance on mercury and seafood consumption is based on cohort studies which used biomarkers of methylmercury exposure (hair, blood) rather dietary fish consumption measures. The ability for FDA to take risk estimates based on mercury concentrations in maternal hair or cord blood and derive a recommended level of fish consumption is based on which of the following:     

         Toxicodynamics

         Toxicokinetics

         Replacement of threshold dose-response model with no-threshold model

         None of the above

Solution

The correct answer is :Toxicokinetics

Reason:Toxicokinetics models are used that incorporates biomarkers to estimate the required level of fish consumption.