Which features of the small GTPase Ran are critical for its

Which features of the small GTPase Ran are critical for its function in nuclear import?

A) its GEF is in the cytosol

B) its GAP is in the cytosol

C) its GEF is in the nucleus

D) answers a and b are both correct

E) answers b and c are both correct

Solution

Answer:

E) answers b and c are both correct

Explanation:

An unequal distribution of Ran/GTP across the nuclear envelope is maintained by the localization of Ran GTPase-activating protein (Ran GAP) in the cytosol and Ran guanine nucleotide exchange factor (Ran GEF) in the nucleus.