What is the Deficiency of B12SolutionIntrinsic factor also k

What is the Deficiency of B12?

Solution

Intrinsic factor also known as gastric intrinsic factor (GIF) and this factor is a glycoprotein. This is going to be produced by the parietal cells of the stomach layers to trigger absorption of vitamin-B12 (cobalamin).

Vitamin B12 is essential for maturation of blood cells and development of nerve cells. This deficiency in neonates and pregnant women can cause neural tube defects. Copper is another co-enzyme that is involved in promotion of immune functioning. This vitamin deficiency is leading to pernicious anemia so that B12- Cobalamin- a cofactor is used in treating pernicious anemia