Which of the following located in the active site of the enz
Which of the following located in the active site of the enzyme chymotrypsin participates in covalent catalysis?
A:The hydrophobic pocket
B:The amide group of glycine
C:The amide group of serine
D:The side chain oxygen of serine
E:Histidine
-An explanation would be appreciated!
Solution
The correct answer is a.
Chymotrypsin is a protease enzyme that cleaves on the C-terminal peptide chains at phenylalanine , tryptophan , and tyrosine. It shows specificity for aromatic amino acids because of its hydrophobic pocket.
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