For each pedigree below determine the most likely mode of in

For each pedigree below, determine the most likely mode of inheritance (i.e, autosomal or sex linked, dominant or recessive) and the probability of the indicated general population and that female child and If a male child Assume that the traits are rare in the general the pedigrees show complete penetrance for the traits. For each pedigree below, determine the most likely mode of inheritance (i.e., autosomal or sex-linked, dominant or recessive) and the probability of the indicated individual being affected. Assume that the traits are rare in the general population and show complete penetrance in the pedigrees.

Solution

1. The first figure:

It is dominant type because traits are inherited from first generation to the next generation and present in every generation. It is also autosomal linked because the second generation where disease inherited, all males offspring are diseased.

The female of parent generation is shown by Aa and male parent is aa

Aa x aa

Aa aa aa Aa

So 50% of males and females were diseased

So in final generation, the probability if a female child= 100% and if a male 100%

The second figure: the second pedigree is also dominant type and autosomal linked. The male offspring have 50% chances to have trait and female offspring have 100% chances to not having trait.

The third figure is autosmal recessive because it is developing in the 2^nd generation. The male offspring and female offspring have 100% chances to not having trait