a Describe the product of the transketolase reaction when th

a. Describe the product of the transketolase reaction when the substrate are a five carbon aldose and a six-carbon ketose. Does it matter which of the substrates binds to the enzyme first?

b. Which coenzyme does transketolase need in order to carry out its catalytic function?

Solution

a) transketolase is mainly participates in pentose pathway which also known as hexose monophospahte pathway. two importent products are formed in these reaction one is pentoses useful for synthesis of nucleic acids and NADPH useful for reductive biosynthesis of fatty acids and steriods. soo when five carbon aldolase binds first it wil give pentoses ..final substrate is ribose 5 phosphate.

when a six carbon ketose binds it wil give NADPH. ..

b.thiamine pyrophosphate ans Mg²⁺ are two coenzyme for transketolase.