Dr z writes an order for Tobramycin 7 mgkgdose IV once daily

Dr. z writes an order for Tobramycin 7 mg/kg/dose IV once daily for a 16 YO cystic fibrosis patient admitted for pulmonary exacerbation. (patient weight a = 41.5 kg, SrCr = 0.35 mg/dl) Please make any recommendations (if any) and write orders accordingly.

Solution

It is 7 mg/Kg. therefore, for 41.5 kg of body weight, it would be 290.5 mg. 290.5mg/ dose. dose is once daily. therefore, 290.5 mg of tobramycin has to be taken daily once.