Ligands bind reversibly to their receptors Select the statem

Ligands bind reversibly to their receptors. Select the statements that describe what would happen if ligands bound irreversibly with their receptors.

A) Pathway will be permanently active.

B)The signal cannot be transduced in the cell.

C)The cell cannot receive new signals.

D)Cell metabolism cannot occur.

Solution

B) The signal cannot be transduced in the cell

They work as antagonists or otherwise called as blockers. They have affinity but they do not have the efficacy for cognate receptors and hence the binding disrupts the interaction and inhibit the function of the agonist. Therefore, the signal remains untranslated into the cell and signal transduction does not occur.