Immunology question Describe and understand the processes of

Immunology question: Describe and understand the processes of class switch and affinity maturation. What controls these processes?

Solution

Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell\'s production of immunoglobulin (antibodies) from one type to another, such as from the isotype IgM to the isotype IgG.

what controls these processes is generally MHC COMPLEX - TCELL antigen presentation complex .... in which a specific type of antibody producing B cell is produced .

In immunology, affinity maturation is the process by which Tfh cell-activated B cells produce antibodies with increased affinity for antigen during the course of an immune response. With repeated exposures to the same antigen, a host will produce antibodies of successively greater affinities.

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