Stress can lead to a problem with the negative feedback loop

Stress can lead to a problem with the negative feedback loop involving the hippocampus and __________.

endorphins

serotonin

testosterone

cortisol

Solution

Cortisol

The human stress response involves a complex signaling pathway between neurons and somatic cells. It involves two peptide hormones, corticotropin-releasing hormone (CRH) and arginine-vassopressin (AVP). Corticotropin-releasing hormone, a short polypeptide, is transported to the anterior pituitary, where it stimulates the secretion of corticotropin which stimulates increased production of corticosteroids including cortisol, impacting the stress response.