exercise And Lope Campos pdf BIOL 1021Feb 2017 After a recen

exercise And Lope Campos pdf BIOL 102:1Feb 2017 After a recent murder took place, a DNA sample was collected at the scene. The sample contains the followinggenotype: Eight suspects were identified by having motive or opportunity to commit the crime. Ast forensic scientist, you were just granted a court order to from those eight individuals (anonymously identified as A-H). The chromosomal sequences from those three loci in the eight suspects are provided below Assume all homozygous in the forensic sample genotype above). Genotype Individual Sequences TATOGATATGCTAT CGAAATCTCTOGOT CGAAA AC TAT ATCTCTCTOGCT CTAGCGAGAGAGCTAG CGAAATC AC TATOGATTATGCTAT CTAGSCGAGAGAGCT TATOGATATATATATGCTAT CTAGCGAGAGAGAGSAGOTAG CGAAATCTCTCGCTAC TATOGA TATGCTAT CTAGCGAGAGAGCTAG TATCGATATGCTAT AGAGAGO TAG CGAAA CTAGCGAGAG. TATOGATATATATATGOTAT CGAAATCTCTOGCTAC CTAGCGAGAGAGOTAG CGAA ATCTCTCTCGCTAC TATOGATATGCTA CTAGCGAGAGAGCTAG which (if any) of suspects A-Hcommitted the murder? As part of your aralysis, it might be useful to write out the genotype (using genetic nomenclature) ofeach suspect How sure are you of your answer to the question above? What concerns (if any) do you have?

Solution

Answer:

Genotypes of the suspects:

A: (GA)3/(GA)3; (TC)3/(TC)3; (AT)4/(AT)4

B: (GA)3/(GA)3; (TC)4/(TC)4; (AT)7/(AT)7

C: (GA)3/(GA)3; (TC)4/(TC)4; (AT)4/(AT)4

D: (GA)5/(GA)5; (TC)3/(TC)3; (AT)4/(AT)7

E: (GA)3/(GA)3; (TC)4/(TC)4; (AT)4/(AT)4

F: (GA)5/(GA)5; (TC)3/(TC)3; (AT)4/(AT)4

G: (GA)3/(GA)3; (TC)3/(TC)3; (AT)4/(AT)7

H: (GA)3/(GA)3; (TC)4/(TC)4; (AT)4/(AT)4

Suspect B appears to have committed the murder after the genotype analysis.

Possible concern for the above suspect is the (AT) repeat which in this case is 7 in contrast to the crime site sample which has 5 (AT) repeats.