Discuss the role of specific algae and fungal toxin in human

Discuss the role of specific algae and fungal toxin in human disease.

Solution

Answer:

Fungal and algal toxins play an important role in causing human diseases.

Role of algae in human disease: Neurotoxic Shellfish Poisoning (NSP) caused by Karenia brevis

NSP is caused by polyether brevetoxins. These compounds are produced by Karenia brevis and causes gastrointestinal and neurological symptoms. Sometimes, toxic aerosol formation may lead to asthma like symptoms. Is is caused by consumption of mollocan shellfish contaminated with brevetoxins.

Role of fungai (fungal toxin) in human disease:

Trichothecenes are mycotoxins produced by fungi (Fusarium) and are powerful inhibitors of protein synthesis. They interact with the components of the ribosome resulting in the dysfunction of the translational machinery. They are generally caused by consumption of grains contaminated with Fusarium sp.

The major effect of trichothecenes include vomiting, reduced feed uptake and immuno-suppression.