Below is the data from humanmouse somatic cell fusions Which
Below is the data from human-mouse somatic cell fusions. Which chromosome contains the gene for the enzyme.
Cell line
Enzyme
Human Chromosomes
1 2 3 4 5 6 7 8 9 10 17 22
A
--
+ -- -- -- + -- -- -- -- + -- --
B
+
+ + -- -- -- -- -- + -- -- + +
C
--
+ -- -- -- + -- -- -- -- -- -- +
D
--
-- -- -- + -- -- -- -- -- -- -- --
E
+
+ -- -- -- -- -- -- -- -- + + --
| Cell line | Enzyme | Human Chromosomes |
| 1 2 3 4 5 6 7 8 9 10 17 22 | ||
| A | -- | + -- -- -- + -- -- -- -- + -- -- |
| B | + | + + -- -- -- -- -- + -- -- + + |
| C | -- | + -- -- -- + -- -- -- -- -- -- + |
| D | -- | -- -- -- + -- -- -- -- -- -- -- -- |
| E | + | + -- -- -- -- -- -- -- -- + + -- |
Solution
The production of enzyme is observed only in two cell lines i.e. B and E due to presence of gene on chromosome-17.
Therefore, the correct option is chromosome-17
