1 Why are G C hydrogen bonds in DNA harder to break than A

1. Why are G – C hydrogen bonds in DNA harder to break than A – T hydrogen bonds?   (10 points)

Solution

The number of hydrogen bonds present linking guanine and cytosine are 3 whereas the number of hydrogen bonds between adenine and thymine are 2 so that more \"stability has acquire by the GC pair\" compared to AT pair during complimentarily in DNA. The high GC content also may trigger high stability to DNA result in high transition temperature (Tm).