Which types of transporters play an Important role In trying

Which types of transporters play an Important role In trying to get drugs across the BBB? ABC transporters Glucose transporters Potassium transporters Lipid transporters

Solution

Lipid diffusion is a mechanism through which lipid soluble drugs which are small molecules of <400kDa weight can enter the Blood brain barrier.

ABC transporters are present in the blood brain barrier that help in drug efflux.They help in keeping the drugs and other neurotoxic substances from passing the BBB by lowering the drug permeability and also help in transporting other toxic metabolites out of BBB.

So the answer is lipid transporters.