Proteins that lack a sorting signal peptide are retained in

Proteins that lack a sorting signal peptide are retained in the? Multiple Choice A nucleus B cytosol C Golgi apparatus D lysosome E endoplasmic reticulum

Solution

1. B. Cytosol

Proteins that lack a sorting signal peptide are retained in the cytosol. Proteins that possess a signal peptide are targeted to the Endoplasmic Reticulum.

2. A. the protein is retained in the cytosol

If a signal sequence is removed by genetic engineering from an ER protein it will be retained in the cytosol.

3. C. endoplasmic reticulum

Translation of proteins that initiate in the cytosol but are destined for other organelles must first associate with the endoplasmic retculum.