What is the second checkpoint for T cell developmentSolution

What is the second checkpoint for T cell development?

Solution

second checkpoint for T cell development is positive and negative selection- Mediated by mature TCR

cells on the lineage are rescued from cell death by binding of their TCR to thymic MHC molecules, allowing CD4+CD8+ thymocytes to undergo positive and negative selection

What is the second checkpoint for T cell development?Solutionsecond checkpoint for T cell development is positive and negative selection- Mediated by mature TCR

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