What would happen to a lysosomal hydrolase that is mutated s

What would happen to a lysosomal hydrolase that is mutated so that its signal patch is no longer two lysines, but 2 Aspartic Acid residues? Where would you find this lysosomal hydrolase? (Hint: what is mutated and probably binding)

Solution

Answer:

The lysosomal hydrolase can be found in lysosomes and these enzymes are going to acts as acid hydrolyses & these are the degradative enzymes of organic biological particulate matter for example, unfolded protein matter and improper useless lipids etc. Normally, the lysine residues are going to get distanced of 34 Å so that mutated version of these enzymes are completely different role to serve as a meticulous critical recognition patch on the surface of the enzymatic proteins,

These hydrolases are going to better work at acidic pHs & includes such as nucleases, proteases, glycosidases and lipases etc. The mutated version of these hydrolases in which there are no presence of two lysine residues result in \"no degradation power of waste biological matter\" even it has 2 aspartic acid residues. Therefore, mutated versions of lysosomal hyrolases with no lysine residues are going to lose their hydrolysis ability as hydrolytic enzymes due to impossibility of SNARE complexes to perform degradation