A clinical trial is planned to compare an experimental medic

A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving seven participants. The objective of the study is to assess how systolic blood pressures change over time if left untreated. Systolic blood pressures are measured at baseline and 4 weeks later. Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance.

Solution

you have to make a paired test, because you want to compare the datas in two different times so
1. first make the experiment (a pilot study)
2. after 4 weeks make again the experiment
3. calculate the difference between the two dates
4. calculate the mean of the differents
5. make the t test
it is important make the hypothesis
Ho: µd=0
H1: µ different µ0

I hope it helps you!!