Which of the following is a correct statement regarding DNA

Which of the following is a correct statement regarding DNA replication in vivo?

Which of the following is a correct statement regarding DNA replication in vivo? A. DNA replication is initiated at the origin of replication in the DNA. B. RNA polymerase requires primers to initiate DNA synthesis. C. Okazaki fragments are the short fragments of DNA that are produced on the lagging strand at the origin of the replication. D. The 5 to 3 direction of DNA synthesis implies that deoxyribonucleotides are added to the 5\' OH group on the growing strand. E. Both A and B F. Both A and C

Solution

Answer: Both A and C

DNA replication is initiated at ori site of a DNA. replication starts at this location. Okazaki fragments are small fragments of DNA formed during replication, these are discontinuous fragments of DNA, so this strand is called as lagging strand. Apart from lagging strand, these are another strand called as leading strand, which synthesis DNA continuously.