epideiomology A study was published this year examining a ne

epideiomology

A study was published this year examining a new screening tool to detect early lung cancer.The screening tool is low dose CT scanning.In this study, two separate observers rated the same 1000 volunteer subjects using low dose CT scanning.Both observers rated 205 subjects as positive for the outcome (non-calcified lung nodules).Both observers rated 764 subjects as negative.One observer found 28 positives when the other did not agree

Compute the overall percent agreement

20.5%

76.4%

96.9%

44.1%

If the Kappa statistic for the two observers above is equal to 0.91, how do you interpret the level of agreement between the two observers?

There is excellent agreement between the two observers

There is moderate agreement between the two observers T

here is poor agreement between the two observers

Agreement cannot be determined

Is the following statement true or false? “The Kappa statistic measures agreement between two tests and adjusts for chance agreement”

True False

In this study, screening was done on all 1000 subjects; there were no subjects without screening.If these subjects were compared to the general population in terms of lung cancer detection and survival, what if any of the following may happen:

Low dose CT scanning may look better than the old method because the volunteers to the study are healthier than the general population Low dose CT scanning may look better than the old method even if the date of death from lung cancer does not change in the subjects because of lead-time Low dose CT scanning may look betterbecause the lung cancers detected are likely to be of longer duration All of the answer choices None of the answer choices

Solution

1)

969 / 1000 = 0.969 = 96.9%

2)

If the Kappa statistic for the two observers above is equal to 0.91, how do you interpret the level of agreement between the two observers?

There is excellent agreement between the two observers

Is the following statement true or false? “The Kappa statistic measures agreement between two tests and adjusts for chance agreement”

TRUE

In this study, screening was done on all 1000 subjects; there were no subjects without screening.If these subjects were compared to the general population in terms of lung cancer detection and survival, what if any of the following may happen:

All of the answer choices