why might eukaryotes employ multiple strategies in order to
Solution
Gene expression :
It is much more complicated in eukaryotic cells than that of prokaryotic cells.
This is due,
a) eukaryotic cells must differentiate into different cell types.
b) they also contain a greater number of genes than prokaryotic cells.
c) there are the transcription and translation sites of eukaryotic DNA .
d) transcription and translation are separated from one another by the nuclear membrane.
e) eukaryotic cells employ a greater variety of control strategies at various steps in both transcription and translation.
strategies of gene expression controls like
.
Control at the DNA level: Eukaryotic cells contain a lot of DNA, and they should firmly crease this DNA to fit it inside the cell nucleus . One outcome of this collapsing, notwithstanding, is that under ordinary conditions, RNA polymerase can\'t tie topromoter arrangements and trigger translation of the related qualities. Along these lines, by specifically unfurling certain portions of their DNA at specific circumstances, eukaryotic cells can control gene expression basically by making promoter successions open to binding by RNA polymerase. What\'s more, a few cells create and interpret various RNA duplicates of critical qualities, which results in the generation of a lot of protein item.
Control at the translation level :In these cells, control at the level of translation is particular and productive. Eukaryotic cells don\'t have administrator groupings like prokaryotic cells do; rather, various types of controller successions happen upstream of eukaryotic promoters and fill in as locales for the official of RNA polymerase. In a few examples, enhancer groupings happen upstream of these controller successions and tie to activator proteins to additionally empower interpretation. Silencer successions that lessen interpretation may likewise be available. These successions tie to repressor proteins and turn translation off by meddling with RNA polymerase .
Loss of control of gene expression
1. may leads to mutation
2. decreased synthesis of protein
3. Alternated cell cycle process and results in many abnormal cellular activities
For example , loss of expression of tumor suppressor genes, may lead to growth of tumors
