You are working to design a skin patch that delivers a drug

You are working to design a skin patch that delivers a drug to the body Examples of patches on the market today include the Nicoderm patch (for helping individuals to quit smoking) and patches that contain hormones, including estrogen and testosterone. The skin patch is thin and flat and has a surface area of 1 in^2. It is placed on the arm with one side up against the skin and the other side exposed to the air. Your intention is to design a patch that To minimize the risk of addiction, the amount of drug delivered decreases as a function of time. You conduct a number of tests to help design and characterize the patch. Your research has shown that the rate that the drug leaves the patch, y, is described by the following formula: y = - 1 mu g/day^2 t + 40 mu g/day where t is the time. Assume that the drug is delivered from the patch to the skin and that no drug is lost to the air. Assuming that the patch is loaded with 800 mu g of drug, how long does it take before the drug is exhausted from the patch? Ignore drug and water losses from the edges (sides) of the patch.

Solution

Accroding to given data if we assume that yhe release rate is zero order reaction it means it remain constant than value of Y remauin constant every time beause transdermal delivery is mostly follow zero order reaction it means it is controlled relese preparation.