Homework SourseThe positive selection process for T lymphocytes that occurs
The positive selection process for T lymphocytes that occurs in the thymus involves selection of T lymphocytes that
a. Have a high affinity for MHC
b. Have a high affinity for MHC and self peptide
c. Have a low affinity for MHC and self peptide
d. Have a low affinity for MHC
The positive selection process for T lymphocytes that occurs in the thymus involves selection of T lymphocytes that
a. Have a high affinity for MHC
b. Have a high affinity for MHC and self peptide
c. Have a low affinity for MHC and self peptide
d. Have a low affinity for MHC
a. Have a high affinity for MHC
b. Have a high affinity for MHC and self peptide
c. Have a low affinity for MHC and self peptide
d. Have a low affinity for MHC
Solution
b. Have a high affinity for MHC and self peptide
Explanation:
Positive selection occurs when double positive T cells bind cortical epithelial cells expressing Class I or Class II MHC plus self peptides with a high enough affinity to get the survival signal.
