The mouse and human genomes share about 75 similarity and mi

The mouse and human genomes share about 75% similarity and mice have 24 chromosomes compared to our 23. Many of the sequences in human chromosome X occur in the mouse chromosome X in the same order. However the sequences of mouse chromosome 1 are found scattered within several human chromosomes. This is true of most mouse to human autosome comparisons. DESCRIBE OR PROVIDE EXPLANATION WHY SEQUENCES OF MOST MOUSE AUTOSOMES ARE FOUND SCATTERED INTO SEVERAL HUMAN AUTOSOMES.

Solution

ANS:

The mouse and human genomes share about 75% similarity and mice have 24 chromosomes Compares to human 23 chromosomes. Many of the sequences in human chromosome x occur in the mouse chromosome x in the same order.

The sequences of most mouse autosomes are found scattered into several human autosomes it is mainly happens due to the difference c value paradox.

In 1940 Dr. Barbara McClintock first discovered half of the human genome is composed with transposable elements or jumping DNA.

C-Value & its paradox:

C-Value represents the total DNA content present in one set of chromosomes that is the genome of an organism is often represented by C-Value.

The amount of the DNA present in different all types of an individual is found to be constant indicting that DNA might be the genetic material and this DNA is not lost during differentiation into different all types.

The C-Value is species specific and the C-Value of an organism increase with increasing the genomic complexity that lower organisms contain relatively less amount of DNA than a higher organism.

There is more than 1000 folds variation in the amount of DNA present from prokaryotic to higher eukaryotic organisms.

The similarities between human and mouse genes from about 70% to 90%, the average similarity is 85% but a lot of variations are present from gene to gene.

In humans 3000 million bases (100,000 genes) are present and mouse contains 3000 million bases (50,000 to 100,000 genes), so most of the gene products are almost identical.