Match the secondary structure with the correct polypeptide s

Match the secondary structure with the correct polypeptide sequence A-C? Explain how you determined your answer. Use the figure as reference.

amphipathic a helix hydrophobic a helix hydrophilic B sheet A. TLNISFQMELDVSIRW B. SLIKSVIEMVDEWFRTFL C. SKDPTGSTOKPN KEGHD hydrophilic a helix amphipathic B sheet hydrophobic B sheet 8 12 15 16 18 13 14 10 17 Helix wheel projection The circle (wheel) is a top-down view of an alpha helix (through the center of the corkscrew). The numbers show the ocation where each side chain projects and repeats with amino acid 19 having the same projection as the first amino acid.

Solution

Amphipathic helix - SLIKSVIEMVDEWFRTFL

Hydrophobic helix SKDPTGSTQKPNKEGHD

Hydrophilic beta sheet - TLNISFQMELDVSIRW

Amphipatic helices, which consist of hydrophobic, non-polar residues on one side from the helical cylinder and hydrophilic and polar residues on the other one side, giving you a hydrophobic moment. That way, they aggregate with other hydrophobe surface.