Adam and Emma are planning on having a baby when they discov

Adam and Emma are planning on having a baby, when they discover that both of their families have a history of alkatonuria. dam\'s sister has this condition and both of Emma\'s grandfather\'s, Ernest and Arthur, did (see pedigree below). Ernest Arthur Adam Emma This disease is passed on through an autosomal recessive allele and makes dark pigment build up in the skin and connective tissues, leading to arthritis. Furthermore, it causes the affected individual\'s urine to turn black when exposed to air. While the disease is not really life threatening, the couple is interested in the probability their child will get the condition. The couple knows you took Biology 121, so they come to you for help; what do you say? a. Impossible to say with the information given b. 1/4 O d 1/16 O e. 1/8

Solution

Answer b. 1/4

Alkaptonuria is an autosomal recessive disease which is due to the lack of enzyme homogenitisic acid oxidase. The genotype of Alkaptonuria person is aa and normal person genotype would be Aa or AA.

c. 3/4

Phenylkenonuria is an autosomal recessive disorder caused due to the amino acid phenylalanine.