All point mutations result in a change to phenotype true fal

All point mutations result in a change to phenotype. true false What is the most probable outcome of a frameshift mutation? a truncated gene product, as with a nonsense mutation a normal-sized gene product, as with a missense mutation an elongated gene product, as with a nonsense mutation A point mutation that occurred within an intron would most likely be characterized as a frameshift mutation deleterious mutation missense mutation silent mutation Which of the following accurately describes the effects of mutations on fitness? Mutations can have a positive, neutral, or negative effect on fitness. Mutations always have a positive effect on fitness. Mutations always have a neutral effect on fitness. Mutations always have a negative effect on fitness.

Solution

B) False

All point mutations donot change the phenotype. Some point mutation lead to silent mutations due to degeneracy of genetic code . These silent point mutations donot change the phenotype as the protein is not changed.

Some point mutation might lead to missence mutation where some amino acids of the protein is changed. This might change the phenotype if the protein modifies to a greater extent. For example change in acidic aminoacid to basic.

c) Frameshift mutation is the mutation that shifts the reading frame. It is due to insertion or deletions. The frame shift mutation might lead to

d) A point mutation in the intron will lead to silent mutation in some cases. If the mutation lies in the splicing side then it might effect the splicing.

e)Mutation can have positive, negative or neutral effect on the fittness of the individual. The mutation effect depends on the change in the protein.