What four bases immediately precede the human PINS linker re

What four bases immediately precede the human PINS linker region motif, and which 4 follow it?

Solution

The N-terminal half of Pins and its relatives contain tetratricopeptide repeats (TPR) that are commonly involved in proteinprotein interactions C terminal contains Gialpha domain. These regions are involved in mitotic spindle formation constitutes spindle apparatus. There are 33 aminoacids sequences involved in binding of proteins . This region before the linker region is responsible for protein protein interaction. The 33 aminoacids forms consesus sequence of 8 bases. 4+4. They are WLGY ( amino acid letter code) and AFAP. WLGY forms hydrophobic pocket , which allows binding of AFAP aminoacid region . So 1st region is WLGY and second is AFGP.